Moko Apt

Menebar Ilmu Pengetahuan

SN-38 Menginduksi Cell Cycle Arrest dan Apoptosis pada kanker Testikular Manusia

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CPT-11 is one of the most widely used camptothecin analogues and is converted to form the active metabolite SN-38. Clinical trials are ongoing to better characterize its spectra of clinical activity, to determine the optimal schedules of administration, and to define the usage in combination with other chemotherapeutic compounds.


Ueno M, Nonaka S, Yamazaki R, Deguchi N, Murai M., SN-38 induces cell cycle arrest and apoptosis in human testicular cancer, Eur Urol. 2002 Oct;42(4):390-7. [Abstract]


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menebar ilmu pengetahuan

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