Moko Apt

Menebar Ilmu Pengetahuan

CML dan Bcr-Abl

Leave a comment


The primary cause of chronic myelogenous leukemia (CML) is the presence of the Philadelphia chromosome, resulting in the oncoprotein Bcr-Abl. The constitutive tyrosine kinase activity of Bcr-Abl, localized intracellularly in the cytoplasm, activates numerous oncogenic signaling pathways.

Author: admin

menebar ilmu pengetahuan

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out / Change )

Twitter picture

You are commenting using your Twitter account. Log Out / Change )

Facebook photo

You are commenting using your Facebook account. Log Out / Change )

Google+ photo

You are commenting using your Google+ account. Log Out / Change )

Connecting to %s